{"id":2120,"date":"2024-01-24T12:29:22","date_gmt":"2024-01-24T11:29:22","guid":{"rendered":"https:\/\/tafalgie.fr\/entreprise\/"},"modified":"2025-10-10T09:45:28","modified_gmt":"2025-10-10T07:45:28","slug":"entreprise","status":"publish","type":"page","link":"https:\/\/tafalgie.fr\/fr\/entreprise\/","title":{"rendered":"Soci\u00e9t\u00e9"},"content":{"rendered":"\n
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SOCIETE<\/p>\n\n\n\n

Une biotech en phase clinique.<\/h1>\n<\/div>\n<\/div><\/div>\n\n\n\n
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Historique<\/h2>\n\n\n\n

Depuis sa cr\u00e9ation en 2020, Tafalgie Therapeutics a r\u00e9uni chercheurs et entrepreneurs ayant pour but commun d\u2019aborder le probl\u00e8me des besoins cliniques non satisfaits dans le domaine de la douleur et d\u2019\u00e9tendre la pharmacop\u00e9e antidouleur existante \u00e0 travers une approche innovante bas\u00e9e sur les propri\u00e9t\u00e9s de la prot\u00e9ine TAFA4 d\u00e9couverte par l\u2019\u00e9quipe du Dr Aziz Moqrich \u00e0 l\u2019IBDM.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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R\u00e9ussites cl\u00e9s<\/h2>\n\n\n\n
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Production selon les bonnes pratiques de fabrication (Good Manufacturing Practice<\/em>, GMP<\/em>)<\/strong><\/p>\n<\/div>\n\n\n\n

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En cours<\/p>\n\n\n\n

Production de lots GMP<\/em> de nos mol\u00e9cules candidates<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Partenariat<\/span><\/p>\n<\/div>\n\n\n\n

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Domaine v\u00e9t\u00e9rinaire<\/p>\n\n\n\n

Augmenter la potentielle transversalit\u00e9 de notre innovation<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Preuve de concept<\/span><\/p>\n<\/div>\n\n\n\n

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Efficacit\u00e9 antalgique<\/p>\n\n\n\n

d\u00e9montr\u00e9e chez des mod\u00e8les pr\u00e9cliniques, sans d\u00e9veloppement d\u2019accoutumance<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Comparaison avec les traitements de r\u00e9f\u00e9rence dans le domaine de la douleur :<\/span><\/p>\n<\/div>\n\n\n\n

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Effet antalgique \u00e9quivalent \u00e0 celui de la morphine et celui des opioides,<\/p>\n\n\n\n

comme la m\u00e9thadone sans les effets ind\u00e9sirables<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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L’\u00e9quipe<\/h2>\n\n\n